As you incorporate big reeds, you will need to remember that their response will be relatively slow. This slowness will be made considerably worse by the equally big valves. As your proposal is for an anglo, you cannot follow the 'single action' design used on english system bass and some baritones, valves are inevitable.
The valves in the chambers are assisted by the valve pins which not only prevent valves being jamed against the chamber walls or pad board/ hole, but also stop the valve being blown too far away from the reed pan base. This means that they can be sucked into place and respond as quickly as their size permits. On the underside of the reed pan valve pins cannot be fitted. Many baritones use valve wires, or sometimes they are called valve springs. Recently I stripped down a double action Edeophone bass. This had the expected very big reeds, and commensurate valves. The valves were made from quite heavy double layered leather and had strong valve wires fitted. Despite this, and although it was not unacceptable, it still played slower than a single action instrument.
This valve design aspect needs to be thought through as much as the reed form that you are choosing.
pic of valve wires attached
Dave